TREM-1 Polyclonal Antibody

Catalog No.: 

Product Name: TREM-1 Polyclonal Antibody

Catalog No.: ALT5133

Reactivity: Human;Rat;Mouse;

Applications: WB;IHC-p;IF/ICC;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:500-2000;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000

Storage Stability: -20°C/1 year

Gene Name: TREM1

Protein Name: Triggering receptor expressed on myeloid cells 1

Human Gene ID: 54210

Human Swiss Prot No.: Q9NP99

Other Name: TREM1; Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354

Subcellular Location: [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Recruited to lipid rafts when activated. .; [Isoform 2]: Secreted .

Expression: Mostly expressed by immune cells of the myeloid lineage, such as monocytes, macrophages, neutrophils and dendritic cells (PubMed:10799849). Expression is associated with a mature stage of myeloid development (PubMed:11922939). Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Isoform 2 was detected in the lung, liver and mature monocytes.

Western Blot analysis of THP-1, mouse heart cells using TREM-1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

For research use only. Not for use in diagnostic procedures.

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