Product Name: Syntenin-2 rabbit pAb
Catalog No.: ALT7859
Applications: WB; ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: SDCBP MDA9 SYCL
Protein Name: Syntenin-2
Human Gene ID: 6386
Human Swiss Prot No.: O00560
Other Name: Syntenin-1 (Melanoma differentiation-associated protein 9;MDA-9;Pro-TGF-alpha cytoplasmic domain-interacting protein 18;TACIP18;Scaffold protein Pbp1;Syndecan-binding protein 1)
Subcellular Location: Cell junction, focal adhesion . Cell junction, adherens junction . Cell membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Nucleus . Melanosome . Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Secreted, extracellular exosome . Membrane raft . Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2) (PubMed:27386966). .
Expression: Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma (at protein level) (PubMed:25893292). Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
For research use only. Not for use in diagnostic procedures.