Syntenin-2 rabbit pAb

Catalog No.: 

Product Name: Syntenin-2 rabbit pAb

Catalog No.: ALT7859

Reactivity: Human;Rat;Dog;Pig

Applications: WB; ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Storage Stability: -20°C/1 year


Protein Name: Syntenin-2

Human Gene ID: 6386

Human Swiss Prot No.: O00560

Other Name: Syntenin-1 (Melanoma differentiation-associated protein 9;MDA-9;Pro-TGF-alpha cytoplasmic domain-interacting protein 18;TACIP18;Scaffold protein Pbp1;Syndecan-binding protein 1)

Subcellular Location: Cell junction, focal adhesion . Cell junction, adherens junction . Cell membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Nucleus . Melanosome . Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Secreted, extracellular exosome . Membrane raft . Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2) (PubMed:27386966). .

Expression: Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma (at protein level) (PubMed:25893292). Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.

For research use only. Not for use in diagnostic procedures.

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