SSTR2 Polyclonal Antibody

Catalog No.: 

Product Name: SSTR2 Polyclonal Antibody

Catalog No.: ALT5740

Reactivity: Human;Mouse;Rat

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: SSTR2

Protein Name: somatostatin receptor 2

Human Gene ID: 6752

Human Swiss Prot No.: P30874

Other Name: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)

Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplasm. Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm.

Expression: Expressed in both pancreatic alpha- and beta-cells (at protein level). Expressed at higher levels in the pancreas than other somatostatin receptors. Also expressed in the cerebrum and kidney and, in lesser amounts, in the jejunum, colon and liver. In the developing nervous system, expressed in the cortex where it is located in the preplate at eaYy stages and is enriched in the outer part of the germinal zone at later stages. In the cerebellum, expressed in the deep part of the external granular layer at gestational week 19. This pattern persists until birth but disappears at adulthood.

Western blot analysis of SH-SY5Y lysis using SSTR2 antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

For research use only. Not for use in diagnostic procedures.

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