SRBS2 rabbit pAb

Catalog No.: 

Product Name: SRBS2 rabbit pAb

Catalog No.: ALT7434

Reactivity: Human; Mouse;Rat

Applications: WB

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:500-2000

Storage Stability: -20°C/1 year

Gene Name: SORBS2 ARGBP2 KIAA0777

Protein Name: SRBS2

Human Gene ID: 8470

Human Swiss Prot No.: O94875

Other Name:

Subcellular Location: Cytoplasm, perinuclear region . Apical cell membrane . Cell junction, focal adhesion . Cell projection, lamellipodium . Found at the Z-disk sarcomeres, stress fibers, dense bodies and focal adhesion. In pancreatic acinar cells, localized preferentially to the apical membrane. Colocalized with vinculin and filamentous actin at focal adhesions and lamellipodia of pancreatic cells. .

Expression: Abundantly expressed in heart. In cardiac muscle cells, located in the Z-disks of sarcomere. Also found, but to a lower extent, in small and large intestine, pancreas, thymus, colon, spleen, prostate, testis, brain, ovary and epithelial cells. In the pancreas, mainly expressed in acinar cells, duct cells and all cell types in islets (at protein level). Tends to be down-regulated in pancreatic adenocarcinomas ans metastases.

Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night

For research use only. Not for use in diagnostic procedures.

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