Product Name: SIRP-α1/β1 Polyclonal Antibody
Catalog No.: ALT5624
Reactivity: Human;Rat;Mouse;
Applications: WB;IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: SIRPA/SIRPB1
Protein Name: Tyrosine-protein phosphatase non-receptor type substrate 1/Signal-regulatory protein beta-1 isoform 3
Human Gene ID: 140885/10326/100653194
Human Swiss Prot No.: P78324/Q5TFQ8
Other Name: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD172a; SIRPB1; Signal-regulatory protein beta-1 isoform 3; SIRP-beta-1 isoform 3
Subcellular Location: Membrane; Single-pass type I membrane protein.
Expression: Ubiquitous. Highly expressed in brain. Detected on myeloid cells, but not T-cells. Detected at lower levels in heart, placenta, lung, testis, ovary, colon, liver, small intestine, prostate, spleen, kidney, skeletal muscle and pancreas.
Western Blot analysis of Hela cells using SIRP-α1/β1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
For research use only. Not for use in diagnostic procedures.