Product Name: Siglec-5/14 Polyclonal Antibody

Catalog No.: ALT5270

Reactivity: Human;Rat;Mouse;

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: SIGLEC5/SIGLEC14

Protein Name: Sialic acid-binding Ig-like lectin 5/Sialic acid-binding Ig-like lectin 14

Human Gene ID: 8778

Human Swiss Prot No.: O15389

Other Name: SIGLEC5; CD33L2; OBBP2; Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding protein 2; CD170; SIGLEC14; Sialic acid-binding Ig-like lectin 14; Siglec-14

Subcellular Location: Membrane; Single-pass type I membrane protein.

Expression: Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing eaYy stages of myelomonocytic differentiation.

Western Blot analysis of L929 cells using Siglec-5/14 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100

For research use only. Not for use in diagnostic procedures.

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