Product Name: PDE4D rabbit pAb
Catalog No.: ALT8039
Reactivity: Human; Mouse;Rat
Applications: WB
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.50% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000
Storage Stability: -20°C/1 year
Gene Name: PDE4D DPDE3
Protein Name: PDE4D
Human Gene ID: 5144
Human Swiss Prot No.: Q08499
Other Name: cAMP-specific 3′,5′-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43)
Subcellular Location: Apical cell membrane . Cytoplasm . Membrane . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity). Colocalized with SHANK2 to the apical membrane of colonic crypt cells. .
Expression: Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. ; [Isoform 6]: Detected in brain. ; [Isoform 8]: Detected in brain, placenta, lung and kidney. ; [Isoform 7]: Detected in heart and skeletal muscle.
For research use only. Not for use in diagnostic procedures.