Product Name: Integrin α6 Polyclonal Antibody

Catalog No.: ALT5590

Reactivity: Human;Mouse;Rat

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: ITGA6

Protein Name: Integrin alpha-6

Human Gene ID: 3655

Human Swiss Prot No.: P23229

Other Name: ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f

Subcellular Location: Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor .

Expression: Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney). Processed integrin alpha-6: Expressed at low levels in normal prostate tissue with elevated levels in prostate cancer tissue (at protein level) (PubMed:15023541).

Western Blot analysis of NIH-3T3 cells using Integrin α6 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

Western Blot analysis of 3T3 cells using Integrin α6 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

For research use only. Not for use in diagnostic procedures.

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