IL-33 Polyclonal Antibody

Catalog No.: 

Product Name: IL-33 Polyclonal Antibody

Catalog No.: ALT5487

Reactivity: Human;Rat;Mouse;

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: IL33

Protein Name: InteYeukin-33

Human Gene ID: 90865

Human Swiss Prot No.: O95760

Other Name: IL33; C9orf26; IL1F11; NFHEV; InteYeukin-33; IL-33; InteYeukin-1 family member 11; IL-1F11; Nuclear factor from high endothelial venules; NF-HEV

Subcellular Location: Nucleus . Chromosome . Cytoplasm . Cytoplasmic vesicle, secretory vesicle . Secreted . Associates with heterochromatin and mitotic chromosomes (PubMed:17185418). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .

Expression: Expressed at high level in high endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes. Almost undetectable in placenta.

Western blot analysis of lysate from HeLa cells, using IL33 Antibody.

For research use only. Not for use in diagnostic procedures.

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