DCNL3 rabbit pAb

Catalog No.: 

Product Name: DCNL3 rabbit pAb

Catalog No.: ALT7767

Reactivity: Human; Mouse;Rat

Applications: WB

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:500-2000

Storage Stability: -20°C/1 year

Gene Name: DCUN1D3

Protein Name: DCNL3

Human Gene ID: 123879

Human Swiss Prot No.: Q8IWE4

Other Name:

Subcellular Location: Cell membrane . Cytoplasm . Nucleus . Cytoplasm, perinuclear region . After UVC treatment, the protein enters to the nucleus gradually (PubMed:18823379). Cell membrane localization is essential for CUL3 neddylation (PubMed:19617556). .

Expression: Tends to be down-regulated in different type of cancers, including lung neuroendocrine carcinoma, thyroid Huerthle cell carcinoma and lung squamous cell carcinoma (PubMed:25349211). Mostly expressed in testis and brain (PubMed:26906416). Highly expressed in liver, bladder and renal normal tissue than their tumor tissue counterparts (PubMed:18823379). Palmitoylation stabilizes DCUN1D3 at the cell membrane (PubMed:19617556).

Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night

For research use only. Not for use in diagnostic procedures.

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