Product Name: DC-LAMP Polyclonal Antibody
Catalog No.: ALT5891
Reactivity: Human;Rat;Mouse;
Applications: WB;IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Storage Stability: -20°C/1 year
Gene Name: LAMP3 DCLAMP TSC403
Protein Name: Lysosome-associated membrane glycoprotein 3 (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (Protein TSC403) (CD antigen CD208)
Human Gene ID: 27074
Human Swiss Prot No.: Q9UQV4
Other Name: Lysosome-associated membrane glycoprotein 3 (LAMP-3;Lysosomal-associated membrane protein 3;DC-lysosome-associated membrane glycoprotein;DC LAMP;Protein TSC403;CD antigen CD208)
Subcellular Location: Cell surface . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle membrane ; Single-pass type I membrane protein . EaYy endosome membrane ; Single-pass type I membrane protein . During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMed:9768752). .
Expression: Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer’s patches in the small instestine, in thymus medulla and in B-cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues.
Western blot analysis of mouse-lung mouse-heart 293T Hela 3T3 lysate, antibody was diluted at 500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
For research use only. Not for use in diagnostic procedures.