Product Name: Cdk4 Polyclonal Antibody
Catalog No.: ALT5198
Reactivity: Human;Mouse;Rat
Applications: IF/ICC;WB;IHC-p;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: IF: 1:50-200 Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: CDK4
Protein Name: Cyclin-dependent kinase 4
Human Gene ID: 1019
Human Swiss Prot No.: P11802
Other Name: CDK4; Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3
Subcellular Location: Cytoplasm . Nucleus . Nucleus membrane . Cytoplasmic when non-complexed. Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) to S phase. Also present in nucleoli and heterochromatin lumps. Colocalizes with RB1 after release into the nucleus. .
Expression: Brain,Muscle,
Western blot analysis of lysate from MCF7 cells, using CDK4 Antibody.
For research use only. Not for use in diagnostic procedures.