Product Name: ZO-2 Polyclonal Antibody
Catalog No.: ALT4993
Reactivity: Human;Mouse;Rat
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: TJP2
Protein Name: Tight junction protein ZO-2
Human Gene ID: 9414
Human Swiss Prot No.: Q9UDY2
Other Name: TJP2; X104; ZO2; Tight junction protein ZO-2; Tight junction protein 2; Zona occludens protein 2; Zonula occludens protein 2
Subcellular Location: Cell junction, adherens junction. Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, tight junction . Nucleus . Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures. .
Expression: This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues.
Western blot analysis of lysate from K562 cells, using ZO-2 antibody.
For research use only. Not for use in diagnostic procedures.