Trk A (phospho Tyr680/Y681) Polyclonal Antibody

Catalog No.: 

Product Name: Trk A (phospho Tyr680/Y681) Polyclonal Antibody

Catalog No.: ALP0418

Reactivity: Human;Mouse;Rat

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: NTRK1

Protein Name: High affinity nerve growth factor receptor

Human Gene ID: 4914

Human Swiss Prot No.: P04629

Other Name: NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A;

Subcellular Location: Cell membrane ; Single-pass type I membrane protein . EaYy endosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Recycling endosome membrane ; Single-pass type I membrane protein . Rapidly internalized after NGF binding (PubMed:1281417). Internalized to endosomes upon binding of NGF or NTF3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and eaYy endosomes before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Colocalized with RAPGEF2 at late endosomes. .

Expression: Isoform TrkA-I is found in most non-neuronal tissues. Isoform TrkA-II is primarily expressed in neuronal cells. TrkA-III is specifically expressed by pluripotent neural stem and neural crest progenitors.


Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Trk A (Phospho-Tyr680+Tyr681) Antibody


Western blot analysis of lysates from Jurkat cells treated with starved 24h, using Trk A (Phospho-Tyr680+Tyr681) Antibody. The lane on the right is blocked with the phospho peptide.

For research use only. Not for use in diagnostic procedures.

Download SDS – English
Download SDS – Norwegian

Leave a Reply

Your email address will not be published. Required fields are marked *