Product Name: TPPP rabbit pAb
Catalog No.: ALT8028
Reactivity: Human; Mouse;Rat
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.39% sodium azide.
Dilution: WB 1:500-2000
Storage Stability: -20°C/1 year
Gene Name: TPPP TPPP1
Protein Name: TPPP
Human Gene ID: 11076
Human Swiss Prot No.: O94811
Other Name: Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha)
Subcellular Location: Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Cytoplasm, cytoskeleton . Nucleus . Cytoplasm, cytoskeleton, spindle . Specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). Mainly localizes to the cytoskeleton (PubMed:18028908). Also found in the nucleus; however, nuclear localization is unclear and requires additional evidences (PubMed:18028908). Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies (PubMed:15590652, PubMed:17027006). During mitosis, colocalizes with LIMK2 at the mitotic spindle (PubMed:22328514). .
Expression: Widely expressed.
Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
For research use only. Not for use in diagnostic procedures.