Product Name: TORC2 rabbit pAb
Catalog No.: ALT8001
Reactivity: Human; Mouse;Rat
Applications: WB
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.12% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000
Storage Stability: -20°C/1 year
Gene Name: CRTC2 TORC2
Protein Name: TORC2
Human Gene ID: 200186
Human Swiss Prot No.: Q53ET0
Other Name: CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)
Subcellular Location: Cytoplasm . Nucleus . Translocated from the nucleus to the cytoplasm on interaction of the phosphorylated form with 14-3-3 protein (PubMed:15454081). In response to cAMP levels and glucagon, relocated to the nucleus (PubMed:15454081). .
Expression: Most abundantly expressed in the thymus. Present in both B and T-lymphocytes. Highly expressed in HEK293T cells and in insulinomas. High levels also in spleen, ovary, muscle and lung, with highest levels in muscle. Lower levels found in brain, colon, heart, kidney, prostate, small intestine and stomach. Weak expression in liver and pancreas.
For research use only. Not for use in diagnostic procedures.