Topo IIα (phospho Thr1343) Polyclonal Antibody

Catalog No.: 

Product Name: Topo IIα (phospho Thr1343) Polyclonal Antibody

Catalog No.: ALP0446

Reactivity: Human;Rat;Mouse;

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: TOP2A

Protein Name: DNA topoisomerase 2-alpha

Human Gene ID: 7153

Human Swiss Prot No.: P11388

Other Name: TOP2A; TOP2; DNA topoisomerase 2-alpha; DNA topoisomerase II; alpha isozyme

Subcellular Location: Cytoplasm . Nucleus, nucleoplasm . Nucleus . Nucleus, nucleolus .

Expression: Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung (PubMed:9155056). Also found in high-grade lymphomas, squamous cell lung tumors and seminomas (PubMed:9155056).

Western blot analysis of lysates from HepG2 cells treated with Ca2+ 40nM 30′, using TOP2A (Phospho-Thr1343) Antibody. The lane on the right is blocked with the phospho peptide.

For research use only. Not for use in diagnostic procedures.

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