Product Name: TNKS1 Polyclonal Antibody
Catalog No.: ALN2269
Reactivity: Human;Mouse
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: TNKS PARP5A PARPL TIN1 TINF1 TNKS1
Protein Name: Tankyrase-1 (TANK1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I)
Human Gene ID: 8658
Human Swiss Prot No.: O95271
Other Name:
Subcellular Location: Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nuclear pore complex . Chromosome, telomere . Cytoplasm, cytoskeleton, spindle pole . Associated with the Golgi and with juxtanuclear SLC2A4/GLUT4-vesicles (PubMed:22864114). A minor proportion is also found at nuclear pore complexes and around the pericentriolar matrix of mitotic centromeres (PubMed:10523501). During interphase, a small fraction of TNKS is found in the nucleus, associated with TERF1 (PubMed:12768206). Localizes to spindle poles at mitosis onset via interaction with NUMA1 (PubMed:12080061). .
Expression: Ubiquitous; highest levels in testis.
For research use only. Not for use in diagnostic procedures.