Product Name: TLR9 Polyclonal Antibody
Catalog No.: ALN2360
Reactivity: Human;Mouse;
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: TLR9 UNQ5798/PRO19605
Protein Name: Toll-like receptor 9 (CD antigen CD289)
Human Gene ID: 54106
Human Swiss Prot No.: Q9NR96
Other Name:
Subcellular Location: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endosome . Lysosome . Cytoplasmic vesicle, phagosome . Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. Exit from the ER requires UNC93B1. Endolysosomal localization is required for proteolytic cleavage and subsequent activation. Intracellular localization of the active receptor may prevent from responding to self nucleic acid. .
Expression: Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.
For research use only. Not for use in diagnostic procedures.