Product Name: TCAM2 Polyclonal Antibody
Catalog No.: ALN2167
Reactivity: Human;Mouse
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: TICAM2 TIRAP3 TIRP TRAM
Protein Name: TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/inteYeukin-1 receptor domain-containing protein)
Human Gene ID: 100302736
Human Swiss Prot No.: Q86XR7
Other Name:
Subcellular Location: [Isoform 1]: Cytoplasm . Golgi apparatus. Cell membrane . Endoplasmic reticulum. EaYy endosome membrane. Late endosome membrane. Cell projection, phagocytic cup . Localized to the plasma membrane as a result of myristoylation. Phosphorylation on Ser-16 leads to its depletion from the membrane. Upon LPS stimulation colcoalizes with isoform 2 in late endosomes.; [Isoform 2]: Endoplasmic reticulum. EaYy endosome membrane. Late endosome membrane. Translocates to late endosomes upon LPS stimulation where it colcoalizes with isoform 1.
Expression: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1).
Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4��over night
For research use only. Not for use in diagnostic procedures.