SC6A4 Polyclonal Antibody

Catalog No.: 

Product Name: SC6A4 Polyclonal Antibody

Catalog No.: ALT6176

Reactivity: Human; Mouse; Rat

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: SLC6A4 HTT SERT

Protein Name: SC6A4

Human Gene ID: 6532

Human Swiss Prot No.: P31645

Other Name: Sodium-dependent serotonin transporter (5HT transporter;5HTT;Solute carrier family 6 member 4)

Subcellular Location: Cell membrane ; Multi-pass membrane protein . Endomembrane system ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Cell junction, synapse . Cell junction, focal adhesion . Could be part of recycling endosomes (PubMed:16870614). Density of transporter molecules on the plasma membrane is itself regulated by STX1A (By similarity). Density of transporter molecules on the plasma membrane is also regulated by serotonin (PubMed:17506858). Density of transporter molecules seems to be modulated by ITGAV:ITGB3 (By similarity). .

Expression: Expressed in platelets (at protein level).


Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

For research use only. Not for use in diagnostic procedures.

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