PTEN (phospho Ser370) Polyclonal Antibody

Catalog No.: 

Product Name: PTEN (phospho Ser370) Polyclonal Antibody

Catalog No.: ALP0237

Reactivity: Human;Mouse;Rat

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: PTEN

Protein Name: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Human Gene ID: 5728

Human Swiss Prot No.: P60484

Other Name: PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog

Subcellular Location: Cytoplasm . Nucleus . Nucleus, PML body . Monoubiquitinated form is nuclear. Nonubiquitinated form is cytoplasmic. Colocalized with PML and USP7 in PML nuclear bodies (PubMed:18716620). XIAP/BIRC4 promotes its nuclear localization (PubMed:19473982). .; [Isoform alpha]: Secreted . May be secreted via a classical signal peptide and reenter into cells with the help of a poly-Arg motif.

Expression: Expressed at a relatively high level in all adult tissues, including heart, brain, placenta, lung, liver, muscle, kidney and pancreas.


Immunohistochemistry analysis of paraffin-embedded human breast cancer, using PTEN (Phospho-Ser370) Antibody. The picture on the right is blocked with the PTEN (Phospho-Ser370) peptide.


Western blot analysis of PTEN (Phospho-Ser370) Antibody. The lane on the right is blocked with the PTEN (Phospho-Ser370) peptide.

For research use only. Not for use in diagnostic procedures.

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