PRC1 Polyclonal Antibody

Catalog No.: 

Product Name: PRC1 Polyclonal Antibody

Catalog No.: ALT5898

Reactivity: Human;Rat;Mouse;

Applications: WB;ELISA;IHC-p

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Storage Stability: -20°C/1 year

Gene Name: PRC1

Protein Name: Protein regulator of cytokinesis 1

Human Gene ID: 9055

Human Swiss Prot No.: O43663

Other Name: Protein regulator of cytokinesis 1

Subcellular Location: Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, spindle pole . Midbody . Chromosome . Colocalized with KIF20B in the nucleus of bladder carcinoma cells at the interphase. Colocalized with KIF20B in bladder carcinoma cells at prophase, metaphase, eaYy anaphase, at the midzone in late anaphase and at the contractile ring in telophase (PubMed:17409436). Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis. Co-localizes with PRC1 in eaYy mitosis and at the spindle midzone from anaphase B to telophase (PubMed:15297875, PubMed:15625105). .

Expression: Overexpressed in bladder cancer cells (PubMed:17409436).

Western blot analysis of lysates from HeLa cells, using PRC1 antibody.

For research use only. Not for use in diagnostic procedures.

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