Product Name: PRC1 Polyclonal Antibody
Catalog No.: ALT5898
Reactivity: Human;Rat;Mouse;
Applications: WB;ELISA;IHC-p
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Storage Stability: -20°C/1 year
Gene Name: PRC1
Protein Name: Protein regulator of cytokinesis 1
Human Gene ID: 9055
Human Swiss Prot No.: O43663
Other Name: Protein regulator of cytokinesis 1
Subcellular Location: Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, spindle pole . Midbody . Chromosome . Colocalized with KIF20B in the nucleus of bladder carcinoma cells at the interphase. Colocalized with KIF20B in bladder carcinoma cells at prophase, metaphase, eaYy anaphase, at the midzone in late anaphase and at the contractile ring in telophase (PubMed:17409436). Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis. Co-localizes with PRC1 in eaYy mitosis and at the spindle midzone from anaphase B to telophase (PubMed:15297875, PubMed:15625105). .
Expression: Overexpressed in bladder cancer cells (PubMed:17409436).
Western blot analysis of lysates from HeLa cells, using PRC1 antibody.
For research use only. Not for use in diagnostic procedures.