Product Name: PP2B-Aα rabbit pAb
Catalog No.: ALT7821
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution: WB 1:500-2000;IHC-p 1:50-300
Storage Stability: -20°C/1 year
Gene Name: PPP3CA CALNA CNA
Protein Name: PP2B-Aα
Human Gene ID: 5530
Human Swiss Prot No.: Q08209
Other Name: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 22.214.171.124;CAM-PRP catalytic subunit;Calmodulin-dependent calcineurin A subunit alpha isoform)
Subcellular Location: Cytoplasm . Cell membrane ; Peripheral membrane protein . Cell membrane, sarcolemma . Cytoplasm, myofibril, sarcomere, Z line . Cell projection, dendritic spine . Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle (By similarity). Recruited to the cell membrane by scaffold protein AKAP5 following L-type Ca(2+)-channel activation (PubMed:22343722). .
Expression: Expressed in keratinocytes (at protein level) (PubMed:29043977). Expressed in lymphoblasts (at protein level) (PubMed:30254215).
Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
For research use only. Not for use in diagnostic procedures.