POLH Polyclonal Antibody

Catalog No.: 

Product Name: POLH Polyclonal Antibody

Catalog No.: ALN1984

Reactivity: Human;Mouse

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Storage Stability: -20°C/1 year

Gene Name: POLH RAD30 RAD30A XPV

Protein Name: DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)

Human Gene ID: 5429

Human Swiss Prot No.: Q9Y253

Other Name:

Subcellular Location: Nucleus . Binding to ubiquitinated PCNA mediates colocalization to replication foci during DNA replication and persists at sites of stalled replication forks following UV irradiation (PubMed:12606586, PubMed:16357261, PubMed:24553286). After UV irradiation, recruited to DNA damage sites within 1 hour, to a maximum of about 80%; this recruitment may not be not restricted to cells active in DNA replication (PubMed:22801543). Colocalizes with TRAIP to nuclear foci (PubMed:24553286). .

Expression: Cervix carcinoma,Epithelium,Skin,

For research use only. Not for use in diagnostic procedures.

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