Product Name: PLEKHG5 rabbit pAb
Catalog No.: ALT8053
Reactivity: Human; Mouse;Rat
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.64% sodium azide.
Dilution: WB 1:500-2000
Storage Stability: -20°C/1 year
Gene Name: PLEKHG5 KIAA0720
Protein Name: PLEKHG5
Human Gene ID: 57449
Human Swiss Prot No.: O94827
Other Name: Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720)
Subcellular Location: Cytoplasm . Cytoplasm, perinuclear region . Cell membrane . Cell junction . Cell projection, lamellipodium . Predominantly cytoplasmic, however when endothelial cells are stimulated with lysophosphatidic acid, PLEKHG5 is found in perinuclear regions and at the cell membrane. Localizes at cell-cell junctions in quiescent endothelial cells, and relocalizes to cytoplasmic vesicle and the leading edge of lamellipodia in migrating endothelial cells. .
Expression: Predominantly expressed in the peripheral nervous system and brain. Highest expression is observed in heart, lung, kidney, testis and moderate expression is present in spleen, pancreas, skeletal muscle, ovary and liver. Weakly expressed in glioblastoma (GBM) cell lines.
For research use only. Not for use in diagnostic procedures.