Product Name: Nrf2 (Acetyl Lys599) Polyclonal Antibody

Catalog No.: ALK0063

Reactivity: Human;Mouse;Rat

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: NFE2L2

Protein Name: Nuclear factor erythroid 2-related factor 2

Human Gene ID: 4780

Human Swiss Prot No.: Q16236

Other Name: NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2

Subcellular Location: Cytoplasm, cytosol . Nucleus . Cytosolic under unstressed conditions: ubiquitinated and degraded by the BCR(KEAP1) E3 ubiquitin ligase complex (PubMed:15601839, PubMed:21196497). Translocates into the nucleus upon induction by electrophilic agents that inactivate the BCR(KEAP1) E3 ubiquitin ligase complex (PubMed:21196497). .

Expression: Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.

Western Blot analysis of A549 cells using Acetyl-Nrf2 (K599) Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100

For research use only. Not for use in diagnostic procedures.

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