Product Name: NISCH rabbit pAb
Catalog No.: ALT7667
Reactivity: Human; Mouse;Rat
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution: WB 1：500-2000
Storage Stability: -20°C/1 year
Gene Name: NISCH IRAS KIAA0975
Protein Name: NISCH
Human Gene ID: 11188
Human Swiss Prot No.: Q9Y2I1
Subcellular Location: Cell membrane. Cytoplasm. EaYy endosome. Recycling endosome. Enriched in the eaYy/sorting and recycling endosomes. Colocalized in eaYy/sorting endosomes with EEA1 and SNX2 and in recycling endosomes with transferrin receptor. Detected in the perinuclear region partially associated with punctate structures (By similarity). Colocalizes with PAK1 in cytoplasm, vesicular structures in the perinuclear area and membrane ruffles (By similarity). Colocalizes with RAC1 in the cytoplasm and vesicles structures (By similarity). Colocalized with MAPK1 and MAPK3 in RVLM neurons (By similarity). .
Expression: Isoform 1, isoform 3 and isoform 4 are expressed in brain. Isoform 1 is expressed in endocrine tissues.
Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
For research use only. Not for use in diagnostic procedures.