LKB1 (phospho Thr189) Polyclonal Antibody

Catalog No.: 

Product Name: LKB1 (phospho Thr189) Polyclonal Antibody

Catalog No.: ALP0328

Reactivity: Human;Mouse

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: STK11

Protein Name: Serine/threonine-protein kinase STK11

Human Gene ID: 6794

Human Swiss Prot No.: Q15831

Other Name: STK11; LKB1; PJS; Serine/threonine-protein kinase STK11; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19

Subcellular Location: Nucleus. Cytoplasm. Membrane . Mitochondrion. A small fraction localizes at membranes (By similarity). Relocates to the cytoplasm when bound to STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta). Translocates to the mitochondrion during apoptosis. PTEN promotes cytoplasmic localization. .; [Isoform 2]: Nucleus . Cytoplasm . Predominantly nuclear, but translocates to the cytoplasm in response to metformin or peroxynitrite treatment.

Expression: Ubiquitously expressed. Strongest expression in testis and fetal liver.

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using LKB1 (Phospho-Thr189) Antibody

Western blot analysis of lysates from NIH/3T3 cells treated with PMA 125ng/ml 30′, using LKB1 (Phospho-Thr189) Antibody. The lane on the right is blocked with the phospho peptide.

For research use only. Not for use in diagnostic procedures.

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