IRF-3 (phospho Ser386) Polyclonal Antibody

Catalog No.: 

Product Name: IRF-3 (phospho Ser386) Polyclonal Antibody

Catalog No.: ALP0438

Reactivity: Human;Rat;Mouse;

Applications: WB;IHC-p

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: WB 1:500-2000;IHC-p 1:50-300

Storage Stability: -20°C/1 year

Gene Name: IRF3

Protein Name: Interferon regulatory factor 3

Human Gene ID: 3661

Human Swiss Prot No.: Q14653

Other Name: IRF3; Interferon regulatory factor 3; IRF-3

Subcellular Location: Cytoplasm . Nucleus . Mitochondrion . Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). .

Expression: Expressed constitutively in a variety of tissues.

Western blot analysis of lysates from HepG2 cells treated with EGF 200ng/ml 30′, using IRF-3 (Phospho-Ser386) Antibody. The lane on the right is blocked with the phospho peptide.

For research use only. Not for use in diagnostic procedures.

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