Product Name: Integrin αIIb rabbit pAb
Catalog No.: ALT7836
Reactivity: Human;Rat;Mouse;
Applications: WB; ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: ITGA2B GP2B ITGAB
Protein Name: Integrin αIIb
Human Gene ID: 3674
Human Swiss Prot No.: P08514
Other Name: Integrin alpha-IIb (GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]
Subcellular Location: Membrane; Single-pass type I membrane protein.
Expression: Isoform 1 and isoform 2 are expressed in platelets and megakaryocytes, but not in reticulocytes. Not detected in Jurkat, nor in U937 cell lines (PubMed:2351656). Isoform 3 is expressed in prostate adenocarcinoma, as well as in several erythroleukemia, prostate adenocarcinoma and melanoma cell lines, including PC-3, DU-145, HEL, WM983A, WM983B and WM35. Not detected in platelets, nor in normal prostate (at protein level) (PubMed:9809974).
For research use only. Not for use in diagnostic procedures.