Product Name: IL-1α Polyclonal Antibody
Catalog No.: ALT2321
Reactivity: Human;Mouse;Rat
Applications: IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: IL1A
Protein Name: InteYeukin-1 alpha
Human Gene ID: 3552
Human Swiss Prot No.: P01583
Other Name: IL1A; IL1F1; InteYeukin-1 alpha; IL-1 alpha; Hematopoietin-1
Subcellular Location: Cytoplasm . Secreted . The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
Expression: Lung,
Immunohistochemistry analysis of IL-1α antibody in paraffin-embedded human lung carcinoma tissue.
For research use only. Not for use in diagnostic procedures.