Product Name: IGF-IR Polyclonal Antibody
Catalog No.: ALT2282
Reactivity: Human;Mouse;Rat
Applications: IF/ICC;WB;IHC-p;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: IF: 1:50-200 Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: IGF1R
Protein Name: Insulin-like growth factor 1 receptor
Human Gene ID: 3480/3643
Human Swiss Prot No.: P08069/P06213
Other Name: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; INSR; Insulin receptor; IR; CD antigen CD220
Subcellular Location: Cell membrane ; Single-pass type I membrane protein .
Expression: Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using IGF1R Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from 293 cells, treated with Insulin, using IGF1R Antibody. The lane on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.