Product Name: GSK3β Polyclonal Antibody
Catalog No.: ALT2082
Reactivity: Human;Mouse;Rat
Applications: IF/ICC;WB;IHC-p;IP;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: IF: 1:50-200 Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: GSK3B
Protein Name: Glycogen synthase kinase-3 beta
Human Gene ID: 2932
Human Swiss Prot No.: P49841
Other Name: GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Subcellular Location: Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .
Expression: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using GSK3 beta Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from 293, COLO205, and HT29 cells, using GSK3 beta Antibody. The lane on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.