Product Name: GANP Polyclonal Antibody
Catalog No.: ALT1847
Reactivity: Human;Mouse
Applications: WB;IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: MCM3AP
Protein Name: 80 kDa MCM3-associated protein
Human Gene ID: 8888
Human Swiss Prot No.: O60318
Other Name: MCM3AP; GANP; KIAA0572; MAP80; 80 kDa MCM3-associated protein; Protein GANP
Subcellular Location: [Isoform GANP]: Nucleus envelope . Nucleus, nuclear pore complex . Nucleus, nucleoplasm . Chromosome . Predominantly located at the nuclear envelope, facing the nucleus interior (PubMed:20005110, PubMed:21195085, PubMed:23591820). Localization at the nuclear pore complex requires NUP153, TPR and ALYREF/ALY (PubMed:23591820, PubMed:22307388). Also found associated with chromatin (PubMed:23652018). In B-cells, targeted to the immunoglobulin variable region genes (PubMed:23652018). .; [Isoform MCM3AP]: Cytoplasm . Nucleus . Translocates into the nucleus in the presence of MCM3 (PubMed:12226073). Associates with chromatin possibly through interaction with MCM3 (PubMed:12226073). .
Expression: Widely expressed (PubMed:11024281). Up-regulated in germinal center B-cells in tonsils (at protein level) (PubMed:11024281).
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using GANP Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from COS7 cells, using GANP Antibody. The lane on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.