G3BP1 (phospho Ser232) Polyclonal Antibody

Catalog No.: 

Product Name: G3BP1 (phospho Ser232) Polyclonal Antibody

Catalog No.: ALP0117

Reactivity: Human;Mouse

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: G3BP1

Protein Name: Ras GTPase-activating protein-binding protein 1

Human Gene ID: 10146

Human Swiss Prot No.: Q13283

Other Name: G3BP1; G3BP; Ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1

Subcellular Location: Cytoplasm, cytosol . Perikaryon . Cytoplasm, Stress granule . Nucleus . Cytoplasmic in proliferating cells (PubMed:11604510). Cytosolic and partially nuclear in resting cells (PubMed:11604510). Recruited to stress granules in response to arsenite treatment (PubMed:12642610, PubMed:20180778). The unphosphorylated form is recruited to stress granules (PubMed:12642610). HRAS signaling contributes to this process by regulating G3BP dephosphorylation (PubMed:12642610). .

Expression: Ubiquitous.

Immunohistochemistry analysis of paraffin-embedded human breast cancer, using G3BP-1 (Phospho-Ser232) Antibody. The picture on the right is blocked with the G3BP-1 (Phospho-Ser232) peptide.

Western blot analysis of extracts from HeLa cells, using G3BP-1 (Phospho-Ser232) Antibody. The lane on the right is treated with the synthesized peptide.

For research use only. Not for use in diagnostic procedures.

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