Flt3 (phospho Tyr599) Polyclonal Antibody

Catalog No.: 

Product Name: Flt3 (phospho Tyr599) Polyclonal Antibody

Catalog No.: ALP0304

Reactivity: Human;Mouse;Monkey

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: FLT3

Protein Name: Receptor-type tyrosine-protein kinase FLT3

Human Gene ID: 2322

Human Swiss Prot No.: P36888

Other Name: FLT3; CD135; FLK2; STK1; Receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; Fetal liver kinase-2; FLK-2; Fms-like tyrosine kinase 3; FLT-3; Stem cell tyrosine kinase 1; STK-1; CD antigen CD135

Subcellular Location: Membrane; Single-pass type I membrane protein. Endoplasmic reticulum lumen. Constitutively activated mutant forms with internal tandem duplications are less efficiently transported to the cell surface and a significant proportion is retained in an immature form in the endoplasmic reticulum lumen. The activated kinase is rapidly targeted for degradation.

Expression: Detected in bone marrow, in hematopoietic stem cells, in myeloid progenitor cells and in granulocyte/macrophage progenitor cells (at protein level). Detected in bone marrow, liver, thymus, spleen and lymph node, and at low levels in kidney and pancreas. Highly expressed in T-cell leukemia.

Western blot analysis of lysates from COS7 cells treated with EGF 200ng/ml 30′, using FLT3 (Phospho-Tyr599) Antibody. The lane on the right is blocked with the phospho peptide.

For research use only. Not for use in diagnostic procedures.

Download SDS – English
Download SDS – Norwegian

Leave a Reply

Your email address will not be published. Required fields are marked *