Product Name: FGFR1/2/3/4 rabbit pAb
Catalog No.: ALT8004
Reactivity: Human; Mouse;Rat
Applications: WB
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.15% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000
Storage Stability: -20°C/1 year
Gene Name: FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR
Protein Name: FGFR1/2/3/4
Human Gene ID: 2260
Human Swiss Prot No.: P11362
Other Name: Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Subcellular Location: Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle. After ligand binding, both receptor and ligand are rapidly internalized. Can translocate to the nucleus after internalization, or by translocation from the endoplasmic reticulum or Golgi apparatus to the cytosol, and from there to the nucleus.
Expression: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells.
Western Blot image of customer’s result
For research use only. Not for use in diagnostic procedures.