Product Name: Eps15 (phospho Tyr849) Polyclonal Antibody
Catalog No.: ALP0469
Reactivity: Human;Mouse;Rat
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: EPS15
Protein Name: Epidermal growth factor receptor substrate 15
Human Gene ID: 2060
Human Swiss Prot No.: P42566
Other Name: EPS15; AF1P; Epidermal growth factor receptor substrate 15; Protein Eps15; Protein AF-1p
Subcellular Location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Recruited to the plasma membrane upon EGFR activation and localizes to coated pits. Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments and in cytoplasmic juxtanuclear structures called aggresomes. .; [Isoform 2]: EaYy endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Colocalizes with HGS on bilayered clathrin coats on endosomes.
Expression: Ubiquitously expressed.
Western Blot analysis of JK cells using Phospho-Eps15 (Y849) Polyclonal Antibody
For research use only. Not for use in diagnostic procedures.