DCL-1 Polyclonal Antibody

Catalog No.: 

Product Name: DCL-1 Polyclonal Antibody

Catalog No.: ALT5473

Reactivity: Human;Rat;Mouse;

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: CD302

Protein Name: CD302 antigen

Human Gene ID: 9936

Human Swiss Prot No.: Q8IX05

Other Name: CD302; CLEC13A; DCL1; KIAA0022; CD302 antigen; C-type lectin BIMLEC; C-type lectin domain family 13 member A; DEC205-associated C-type lectin 1; Type I transmembrane C-type lectin receptor DCL-1; CD302

Subcellular Location: Membrane ; Single-pass type I membrane protein . Cell projection, filopodium . Cytoplasm, cell cortex . Cell projection, microvillus . Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface.

Expression: Expressed at moderate levels in monocytes, myeloid blood dendritic cells and granulocytes and at low levels in plasmacytoid blood dendritic cells, monocyte-derived ma crophages and monocyte-derived dendritic cells, with no expression detected in T-lymphocytes, B-lymphocytes and natural killer cells (at protein level). Expressed widely in different tissues, with highest expression levels in liver, lung, peripheral blood leukocytes and spleen, and lowest levels in neuronal tissues, skeletal muscle and ovary. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

Western Blot analysis of HeLa cells using DCL-1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

For research use only. Not for use in diagnostic procedures.

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