Product Name: CtIP Polyclonal Antibody
Catalog No.: ALT1152
Reactivity: Human;Mouse
Applications: IHC-p;IF(paraffin section);WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: RBBP8
Protein Name: DNA endonuclease RBBP8
Human Gene ID: 5932
Human Swiss Prot No.: Q99708
Other Name: RBBP8; CTIP; DNA endonuclease RBBP8; CtBP-interacting protein; CtIP; Retinoblastoma-binding protein 8; RBBP-8; Retinoblastoma-interacting protein and myosin-like; RIM; Sporulation in the absence of SPO11 protein 2 homolog; SAE2
Subcellular Location: Nucleus . Chromosome . Associates with sites of DNA damage in S/G2 phase (PubMed:10764811, PubMed:25349192). Ubiquitinated RBBP8 binds to chromatin following DNA damage (PubMed:16818604). .
Expression: Expressed in ER-positive breast cancer lines, but tends to be down-regulated ER-negative cells (at protein level).
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CTIP Antibody. The picture on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.