Product Name: CRNN Polyclonal Antibody
Catalog No.: ALN2371
Reactivity: Human;Rat;Mouse;
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Storage Stability: -20°C/1 year
Gene Name: CRNN C1orf10 DRC1 PDRC1 SEP53
Protein Name: Cornulin (53 kDa putative calcium-binding protein) (53 kDa squamous epithelial-induced stress protein) (58 kDa heat shock protein) (Squamous epithelial heat shock protein 53) (Tumor-related protein)
Human Gene ID: 49860
Human Swiss Prot No.: Q9UBG3
Other Name:
Subcellular Location: Cytoplasm . Does not colocalize with TGM1.
Expression: Expressed in the basal skin layer (at protein level) (PubMed:30009832). Squamous epithelia cell-specific. Expressed in the esophagus (periphery of the cells of the granular and the upper spinous layers), foreskin (granular and lower cornified cells), scalp skin (granular layer), inner root sheath of the hair follicle and in primary keratinocytes (at protein level). Expressed in the squamous epithelium of the cervix, esophagus, foreskin and larynx. Expressed in the fetal bladder and scalp skin. Expressed at very low levels in the lung, kidney, uterus, skeletal muscle, heart and fetal brain. Undetectable or barely detectable in esophageal and oral squamous cell carcinoma compared with the matched adjacent normal esophageal mucosa. Undetectable or barely detectable in larynx and esophagus from patients with pH-documented laryngopharyngeal reflux (LPR).
For research use only. Not for use in diagnostic procedures.