Product Name: Cleaved-Notch 2 (A1734) Polyclonal Antibody
Catalog No.: ALC0068
Reactivity: Human;Mouse;Rat
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: NOTCH2
Protein Name: Neurogenic locus notch homolog protein 2
Human Gene ID: 4853
Human Swiss Prot No.: Q04721
Other Name: NOTCH2; Neurogenic locus notch homolog protein 2; Notch 2; hN2
Subcellular Location: [Notch 2 extracellular truncation]: Cell membrane ; Single-pass type I membrane protein .; [Notch 2 intracellular domain]: Nucleus . Cytoplasm . Following proteolytical processing NICD is translocated to the nucleus. Retained at the cytoplasm by TCIM (PubMed:25985737). .
Expression: Expressed in the brain, heart, kidney, lung, skeletal muscle and liver. Ubiquitously expressed in the embryo.
Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using NOTCH2 (Cleaved-Ala1734) Antibody. The lane on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.