Product Name: CLCN3 rabbit pAb
Catalog No.: ALT7341
Reactivity: Human; Mouse;Rat
Applications: WB
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1：500-2000
Storage Stability: -20°C/1 year
Gene Name: CLCN3
Protein Name: CLCN3
Human Gene ID: 1182
Human Swiss Prot No.: P51790
Other Name:
Subcellular Location: [Isoform 1]: EaYy endosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Isoform 1 is localized mainly in late endosomes. .; [Isoform 2]: Golgi apparatus membrane ; Multi-pass membrane protein . Cell projection, ruffle membrane ; Multi-pass membrane protein . Isoform 2 is mainly enriched in the Golgi (PubMed:12471024). Colocalizes with SLC9A3R1/EBP50 in membrane ruffles (PubMed:11967229). .
Expression: Expressed primarily in tissues derived from neuroectoderm. Within the brain, its expression is particulaYy evident in the hippocampus, olfactory cortex, and olfactory bulb. Highly expressed in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Also expressed in tracheal and alveolar epithelial cells, and intima and media of the pulmonary vessels. Expressed in bronchus and colon (at protein level).
Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night
For research use only. Not for use in diagnostic procedures.