Product Name: CKAP5 rabbit pAb
Catalog No.: ALT6302
Reactivity: Human; Mouse
Applications: WB
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: WB 1：500-2000
Storage Stability: -20°C/1 year
Gene Name: CKAP5 KIAA0097
Protein Name: CKAP5
Human Gene ID: 9793
Human Swiss Prot No.: Q14008
Other Name:
Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Detected on centrosomes and kinetochores during interphase and mitosis independently from TACC3 and clathrin. Located to spindle poles and microtubules during mitosis. In complex with TACC3 localized to microtubule plus-ends in mitosis and interphase. In complex with TACC3 and clathrin localized to inter-microtubule bridges in mitotic spindles. Accumulation sites at microtubule plus ends protruded approximately 100 nm from MAPRE1/EB1 sites in interphase cells. .
Expression: Overexpressed in hepatomas and colonic tumors. Also expressed in skeletal muscle, brain, heart, placenta, lung, liver, kidney and pancreas. Expression is elevated in the brain; highly expressed in the Purkinje cell bodies of the cerebellum.
Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
For research use only. Not for use in diagnostic procedures.