CD6 Polyclonal Antibody

Catalog No.: 

Product Name: CD6 Polyclonal Antibody

Catalog No.: ALT5577

Reactivity: Human;Rat;Mouse;

Applications: WB;IHC-p;IF(paraffin section);ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: CD6

Protein Name: T-cell differentiation antigen CD6

Human Gene ID: 923

Human Swiss Prot No.: P30203

Other Name: CD6; T-cell differentiation antigen CD6; T12; TP120; CD6

Subcellular Location: Cell membrane ; Single-pass type I membrane protein . Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with the TCR/CD3 complex at the immunological synapse (PubMed:15294938). .; [Soluble CD6]: Secreted . The origins of the secreted form are not clear, but it might be created by proteolytic shedding of the ectodomain. .

Expression: Detected on thymocytes (PubMed:15294938). Detected on peripheral blood T-cells (PubMed:15048703, PubMed:16352806). Detected on natural killer (NK) cells (PubMed:16352806). Soluble CD6 is detected in blood serum (at protein level) (PubMed:17601777). Detected in spleen, thymus, appendix, lymph node and peripheral blood leukocytes (PubMed:9013954). Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.


Western Blot analysis of 293 cells using CD6 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000


Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100

For research use only. Not for use in diagnostic procedures.

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