Product Name: CB2 Polyclonal Antibody
Catalog No.: ALT0688
Reactivity: Human;Rat;Mouse;
Applications: WB;IF/ICC;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: CNR2
Protein Name: Cannabinoid receptor 2
Human Gene ID: 1269
Human Swiss Prot No.: P34972
Other Name: CNR2; Cannabinoid receptor 2; CB-2; CB2; hCB2; CX5
Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell projection, dendrite . Perikaryon . Localizes to apical dendrite of pyramidal neurons. .
Expression: Preferentially expressed in cells of the immune system with higher expression in B-cells and NK cells (at protein level). Expressed in skin in suprabasal layers and hair follicles (at protein level). Highly expressed in tonsil and to a lower extent in spleen, peripheral blood mononuclear cells, and thymus. PubMed:14657172 could not detect expression in normal brain. Expressed in brain by perivascular microglial cells and dorsal root ganglion sensory neurons (at protein level). Two isoforms are produced by alternative promoter usage and differ only in the 5′ UTR: isoform CB2A is observed predominantly in testis with some expression in brain, while isoform CB2B is predominant in spleen and leukocytes.
Western blot analysis of lysates from COLO205 cells, using CNR2 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HT-29 cells using CNR2 antibody.
For research use only. Not for use in diagnostic procedures.