Btk (phospho Tyr223) Polyclonal Antibody

Catalog No.: 

Product Name: Btk (phospho Tyr223) Polyclonal Antibody

Catalog No.: ALP0287

Reactivity: Human;Mouse;Rat

Applications: WB;ELISA

Source: Polyclonal, Rabbit,IgG

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Storage Stability: -20°C/1 year

Gene Name: BTK

Protein Name: Tyrosine-protein kinase BTK

Human Gene ID: 695

Human Swiss Prot No.: Q06187

Other Name: BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase

Subcellular Location: Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. In steady state, BTK is predominantly cytosolic. Following B-cell receptor (BCR) engagement by antigen, translocates to the plasma membrane through its PH domain. Plasma membrane localization is a critical step in the activation of BTK. A fraction of BTK also shuttles between the nucleus and the cytoplasm, and nuclear export is mediated by the nuclear export receptor CRM1.

Expression: Predominantly expressed in B-lymphocytes.

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using BTK (Phospho-Tyr223) Antibody

Western blot analysis of lysates from HeLa cells treated with Serum 10% 15′, using BTK (Phospho-Tyr223) Antibody. The lane on the right is blocked with the phospho peptide.

For research use only. Not for use in diagnostic procedures.

Download SDS – English
Download SDS – Norwegian

Leave a Reply

Your email address will not be published. Required fields are marked *