Product Name: ATR Polyclonal Antibody
Catalog No.: ALT0416
Reactivity: Human;Rat;Mouse;
Applications: WB;IHC-p;IF(paraffin section);ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: ATR
Protein Name: Serine/threonine-protein kinase ATR
Human Gene ID: 545
Human Swiss Prot No.: Q13535
Other Name: ATR; FRP1; Serine/threonine-protein kinase ATR; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1
Subcellular Location: Nucleus . Chromosome . Depending on the cell type, it can also be found in PML nuclear bodies. Recruited to chromatin during S-phase. Redistributes to discrete nuclear foci upon DNA damage, hypoxia or replication fork stalling.
Expression: Ubiquitous, with highest expression in testis. Isoform 2 is found in pancreas, placenta and liver but not in heart, testis and ovary.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using ATR Antibody. The picture on the right is blocked with the synthesized peptide.
For research use only. Not for use in diagnostic procedures.