Product Name: Atg16 Polyclonal Antibody
Catalog No.: ALT0391
Reactivity: Human;Rat;Mouse;
Applications: WB;ELISA
Source: Polyclonal, Rabbit,IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration:1 mg/ml
Dilution: Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Storage Stability: -20°C/1 year
Gene Name: ATG16L1
Protein Name: Autophagy-related protein 16-1
Human Gene ID: 55054
Human Swiss Prot No.: Q676U5
Other Name: ATG16L1; APG16L; Autophagy-related protein 16-1; APG16-like 1
Subcellular Location: Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Recruited to omegasomes membranes by WIPI2 (By similarity). Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (By similarity). Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5 (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity). Upon activation of non-canonical autophagy, recruited to single-membrane endolysosomal compartments (PubMed:29317426). .
Expression: Brain,Colon,Epithelium,Fetal brain,Human lung,Mammary gland,Placenta,Small
Western Blot analysis of Jurkat using Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
For research use only. Not for use in diagnostic procedures.